Hall of Fame

Accounts of Chemical Research. 2024;57(22):3266. Chemical-driven amyloid clearance for therapeutics and diagnostics of Alzheimer’s disease. Kim H, Kim Y*. link Cover

Angewandte Chemie International Edition. 2024. ePub ahead. Drug discovery and screening tool development for tauopathies by focusing on pathogenic tau repeat 3 oligomers. Yoon S, Kim HY, Park S, Cha M, Kim K, Lee S, Kim JM, Bhang S, Kim Y*. link Interview Webinar

Nature Communications. 2024;15:1004. Early onset diagnosis in Alzheimer’s disease patients via amyloid-β oligomers-sensing probe in cerebrospinal fluid. link 

Angewandte Chemie International Edition. 2023;62(7):e202210209. Amyloid against amyloid: dimeric amyloid fragment ameliorates cognitive impairments by direct clearance of oligomers and plaques. link

Advanced Materials. 2023;35(3):2207719. A therapeutic nanovaccine that generates anti-amyloid antibodies and amyloid-specific regulatory T cells for Alzheimer's disease. link

Advanced Science. 2022;9(12):e2104542. Chemical-driven outflow of dissociated amyloid burden from brain to blood. link Interview

Angewandte Chemie International Edition. 2020;59(51):22994. Rhizolutin, a novel 7/10/6‐tricyclic dilactone, dissociates misfolded protein aggregates and reduces apoptosis/inflammation associated with Alzheimer’s disease. link Interview

Angewandte Chemie International Edition. 2020;59(28):11491 . Discovery of chemicals to either clear or indicate amyloid aggregates by targeting memory‐impairing anti‐parallel Aβ dimers. link Interview Webinar

Experimental & Molecular Medicine. 2019;51:53. Diagnosis of Alzheimer’s disease utilizing amyloid and tau as fluid biomarkers. link

ACS Central Science. 2019;5(2):209. Frontiers in probing Alzheimer’s disease biomarkers with fluorescent small molecules. link

Science Advances. 2019;5(4):eaav1388. Comparative analyses of plasma amyloid-β levels in heterogeneous and monomerized states by interdigitated microelectrode sensor system. link Interview

EMBO Molecular Medicine. 2017;9:61. Nec-1 alleviates cognitive impairment with reduction of Aβ and tau abnormalities in APP/PS1 mice. link

Journal of Visualized Experiments. 2016;109:e53308. Intracerebroventricular injection of amyloid-β peptides in normal mice to acutely induce Alzheimer-like cognitive deficits. link

Nature Communications. 2015;6:8997. EPPS rescues hippocampus-dependent cognitive deficits in APP/PS1 mice by disaggregation of amyloid-β oligomers and plaques. link Interview Webinar

Scientific Reports. 2014;4:7467. Taurine in drinking water recovers learning and memory in the adult APP/PS1 mouse model of Alzheimer's disease. link

Amyloid. 2013;20(1):7-12. Amelioration of Alzheimer's disease by neuroprotective effect of sulforaphane in animal model. link

Biochemistry. 2006;45(31):9434-44. Targeting heat shock proteins on cancer cells: selection, characterization, and cell-penetrating properties of a peptidic GRP78 ligand. link