Publications

2024

1. Angewandte Chemie International Edition. In Preparation. Lee D et al.

2. Bulletin of the Korean Chemical Society. In Preparation. Lee et al.

3. ACS Chemical Neuroscience. In Preparation. Lee S  et al.

4. ACS Pharmacology & Translational Science. In Preparation. Shin H  et al.

5. ACS Chemical Neuroscience. In Preparation. Kim K  et al.

6. Angewandte Chemie International Edition. In Preparation. Cha M et al.

7. Nature Communications. In Preparation. Cho I et al.

8. Nature Communications. In Preparation. Cho I et al.

9. Alzheimer’s Research & Therapy. Under Review. Kim et al.

10. Accounts of Chemical Research. 2024;57(22):3266. Chemical-driven amyloid clearance for therapeutics and diagnostics of Alzheimer’s disease. Kim H, Kim Y*. link (Cover link)

11. Angewandte Chemie International Edition. 2024. ePub ahead. Drug discovery and screening tool development for tauopathies by focusing on pathogenic tau repeat 3 oligomers. Yoon S, Kim HY, Park S, Cha M, Kim K, Lee S, Kim JM, Bhang S, Kim Y*. link

12. ACS Pharmacology & Translational Science. 2024;7(9):2650. Modulation of amyloid and tau aggregation to alleviate cognitive impairment in a transgenic mouse model of Alzheimer’s disease. Park S, Shin J, Kim K, Kim D, Lee WS, Lee J, Cho I, Park IW, Yoon S, Lee S, Kim HY*, Lee JH*, Hong KB*, Kim Y*. link  (Front Cover link)

13. Molecular Pharmaceutics. 2024;21(7):3330. Chemically driven clearance of amyloid aggregates by polyfunctionalized furo[2,3-b:4,5-b′]dipyridine–chalcone hybrids to ameliorate memory in an Alzheimer mouse model. Cha M, Kim S, Jung E, Cho I, Park IW, Yoon S, Ye S, Lee S, Kim JM, Kim HY, Maeng H-J, Kim I*, Kim Y*. link

14. Nature Communications. 2024;15:1004. Early onset diagnosis in Alzheimer’s disease patients via amyloid-β oligomers-sensing probe in cerebrospinal fluid. An J, Kim K, Lim HJ, Kim HY, Shin J, Park IW, Cho I, Kim HY, Kim S, McLean C, Choi K, Kim Y*, Lee KH*, Kim JS*. link, 100th Paper of Kim lab

2023

15. ACS Chemical Neuroscience. 2023;14(17):3025. Benzo[d]imidazole-pyrrolo[1,2-a]pyrazine hybrids ameliorate amyloid aggregates in the brain of Alzheimer transgenic mice. Cha M, Dagar A, Lee S, Cho I, Lee D, Kim K, Park IW, Yoon S, Kim HY, Kim I*, Kim Y*. link

16. ChemBioChem. 2023;24(19):e202300328. Failure, success, and future direction of Alzheimer drugs targeting amyloid-β cascade: pros and cons of chemical and biological modalities. Kim J, Jeon H, Kim HY*, Kim Y*. link

17. Scientific Reports. 2023;13:10889. Carprofen alleviates Alzheimer-like phenotypes of 5XFAD transgenic mice by targeting the pathological hallmarks induced by amyloid-β aggregation. Lee D, Ryoo JE, Hong S, Kim HY, Kim Y*. link

18. Pharmacological Research.2023;194:106836. Inhibition of CXXC5 function rescues Alzheimer’s disease phenotypes by restoring Wnt/β-catenin signaling pathway.Yoon M, Kim H, Shin H, Lee HY, Kang M-J, Park S-H, Han G, Kim Y*, Choi K-Y*. link

19. ACS Chemical Neuroscience. 2023;14(11):2016. 4-Acyl-3,4-dihydropyrrolo[1,2-a]pyrazine derivative rescued the hippocampal-dependent cognitive decline of 5XFAD transgenic mice by dissociating soluble and insoluble Aβ aggregates. Lee S, Dagar A, Cho I, Kim K, Park IW, Yoon S, Cha M, Shin J, KIM HY, Kim I*, Kim Y*. link

20. Biosensors and Bioelectronics. 2023;226:115117. Nanotechnology and machine learning enable circulating tumor cells as a reliable biomarker for radiotherapy responses of gastrointestinal cancer patients. Poellmann MJ, Bu J, Liu S, Wang AZ, Seyedin SN, Chandrasekharan C, Hong H, Kim Y, Caster J, Hong S*. link

21. Marine Drugs. 2023;21(2):67. Glycosylated and succinylated macrocyclic lactones with amyloid-β-aggregation-regulating activity from a marine bacillus sp. Cui J, Ye S, Shin D, Cho I, Kim HY, Kwon Y, Park K, Nam S-J, Kim Y*, Oh D-C. link

22. Scientific Reports. 2023;13:505. Solid-phase synthesis and pathological evaluation of pyroglutamate amyloid-β3-42 peptide. Cho I, Lee H, Lee D, Park IW, Yoon S, Kim HY*, Kim Y*. link

23. ACS Chemical Neuroscience. 2023;14(1):9. Immobilized amyloid hexamer fragments to map active sites of amyloid-targeting chemicals. Cho I, Yoon S, Park S, Hong SW, Cho E, Kim E, Kim HY*, Kim Y*.  link (Front Cover link)

24. Angewandte Chemie International Edition. 2023;62(7):e202210209. Amyloid against amyloid: dimeric amyloid fragment ameliorates cognitive impairments by direct clearance of oligomers and plaques. Lee HY, Baek S, Cha M, Yang S-H, Cho I, Shin H, LEe S, Kim HY, Lee S, Shin J, Lee D, Kim K, Park I, Yoon S, Kim J, Park S, Kim SM, Kim KE, Kim HJ, Oh M-S, Lee G-H, Yu B-Y, Kanna P, Park K, Kim Y*. link

25. Advanced Materials. 2023;35(3):2207719. A therapeutic nanovaccine that generates anti-amyloid antibodies and amyloid-specific regulatory T cells for Alzheimer's disease. Jung M, Lee S, Park S. Hong J, Kim C, Cho I, Sohn HS, Kim K, Park IW, Yoon S, Kwon S, Shin J, Lee D, Kang M, Go S, Moon S, Chung Y, Kim Y*, Kim B-S*. link

2022

26. Alzheimer’s Research & Therapy. 2022;14:177. Aryloxypropanolamine targets amyloid aggregates and reverses Alzheimer-like phenotypes in Alzheimer mouse models. Lee HY, Yoon S, Lee JH, Park K, Jung Y, Cho I, Lee D, Shin J, Kim K, Kim S, Kim J, Kim K, Han SH, Kim SM, Kim HJ, Kim HY, Kim I*, Kim Y*. link

27. Experimental Neurobiology. 2022;31(2):65. Physiological Roles of Monomeric Amyloid-β and Implications for Alzheimer’s Disease Therapeutics. Jeong H, Shin H, Hong S, Kim Y*. link

28. Advanced Science. 2022;9(12):e2104542. Chemical-driven outflow of dissociated amyloid burden from brain to blood. Lee D, Kim HV, Kim HY*, Kim Y*. link (Journal Cover link)

29. WIREs Nanomedicine and Nanobiotechnology. 2022;14(3):e1770. Branched, dendritic, and hyperbranched polymers in liquid biopsy device design. Poellmann MJ, Rawding P, Kim D, Bu J, Kim Y, Hong S*. link

30. WIREs Nanomedicine and Nanobiotechnology. 2022;14(2):e1752. Dendrimers for cancer immunotherapy: Avidity-based drug delivery vehicles for effective anti-tumor immune response. Rawding PA, Bu J, Wang J, Kim DW, Drelich AJ, Kim Y, Hong S*. link

2021

31. RSC Medicinal Chemistry. 2021;12:1926. Anti-amyloidogenic indolizino[3,2-c]quinolines as imaging probes differentiating dense-core, diffuse, and coronal plaques of amyloid-β. Kim K, Lee JH, Kim S, Lee S, Lee D, Kim HY, Kim I*, Kim Y*. link

32. Biomedical Engineering Letters. 2021;11:287. Bias-generating factors in biofluid amyloid-β measurements for Alzheimer’s disease diagnosis. Park S, Kim Y*. link

33. Applied Sciences. 2021;11(13):5878. Validation of Fucoxanthin from Microalgae Phaeodactylum tricornutum for the Detection of Amyloid Burden in Transgenic Mouse Models of Alzheimer’s Disease. Lee A-H, Hong S-C, Park I, Yoon S, Kim Y, Kim J*, Yang S-H*. link

34. Scientific Reports. 2021;11:12043. Quinacrine directly dissociates amyloid plaques in the brain of 5XFAD transgenic mouse model of Alzheimer’s disease. Park S, Kim HY, Oh H-A, Shin J, Park IW, Yoon S, Woo DH, Kim Y*. link

35. The Journal of Organic Chemistry. 2021;86(16):11149. Azetidine-Bearing Non-Ribosomal Peptides, Bonnevillamides D and E, Isolated from a Carrion Beetle-Associated Actinomycete. Shin Y-H, Ban YH, Shin J, Park IW, Yoon S, Ko K, Shin J, Nam S-J, Winter JM, Kim Y, Yoon YJ, Oh D-C*. link

36. Scientific Reports. 2021;11:1617. Thioflavin-positive tau aggregates complicating quantification of amyloid plaques in the brain of 5XFAD transgenic mouse model. Shin J, Park S, Lee H, Kim Y*. link

37. Journal of Alzheimer’s Disease Reports. 2021;5(1):7. Borrelidin from Saltern-Derived Halophilic Nocardiopsis sp. Dissociates Amyloid-β and Tau Fibrils. Shin J, Yang S-H, Du YE, Park K, Kim D, Shin D, Kim J, Kim SH, Kim YK, Shin J, Oh D-C*, Kim Y*. link

38. ACS Chemical Neuroscience. 2021;12(1):99. Orally Administered Benzofuran Derivative Disaggregated Aβ Plaques and Oligomers in the Brain of 5XFAD Alzheimer Transgenic Mouse. Kim D, Bae G, Kim HY, Jeon H, Kim K, Shin J, Lee S, Hong S, Kim I*, Kim Y*. link

2020

39. PLoS One. 2020;15(12):e0243041. Fluorescent indolizine derivative YI-13 detects amyloid-β monomers, dimers, and plaques in the brain of 5XFAD Alzheimer transgenic mouse model. Kim D, Lee JH, Kim HY, Shin J, Kim K, Lee S, Park J, Kim I*, Kim Y*. link

40. Nature Neuroscience. 2020;23:1555. Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer’s disease via H2O2 - production. Chun H, Im H, Kang YJ, Kim Y, Shin YK, Won W, Lim J, Ju Y, Park YM, Kim S, Lee SE, Lee J, Woo J, Hwang Y, Cho H, Jo S, Park J-H, Kim D, Kim DY, Seo J-S, Gwag BJ, Kim YS, Park KD, Kaang B-K, Cho H, Ryu H, Lee CJ*.  link

41. Scientific Reports. 2020;10:17622. Hair growth promotion by necrostatin-1s. Zheng M, Choi N, Jang Y, Kwak DE, Kim Y, Kim W-S, Oh SH, Sung J-H*. link

42. PLoS One. 2020;15(10):e0240608. Bicine promotes rapid formation of β-sheet-rich amyloid-β fibrils. Kim HY, Lee H, Lee JK, Kim HV, Kim K-S, Kim Y*. link

43. Angewandte Chemie International Edition. 2020;59(51):22994. Rhizolutin, a novel 7/10/6‐tricyclic dilactone, dissociates misfolded protein aggregates and reduces apoptosis/inflammation associated with Alzheimer’s disease. Kwon Y, Shin J, Nam K, An JS, Yang S-H, Hong S-H, Bae M, Moon K, Cho Y, Woo J, Park K, Kim K, Shin J, Kim B-Y, Kim Y*, Oh D-C*. (Selected as Very Important Paper) link

44. BMC Neurology. 2020;20:293. Elevated plasma biomarkers of inflammation in acute ischemic stroke patients with underlying dementia. Choi DW*, Kim TS, Kim Y, Kim DJ. link

45. Scientific Reports. 2020;10:11234. Longitudinal profiling of oligomeric Aβ in human nasal discharge reflecting cognitive decline in probable Alzheimer’s disease. Yoo S-J, Son G, Bae J, Yoo YK, Park D, Baek SY, Chang K-A, Suh Y-H, Lee Y-B, Hwang KS, Kim Y, Moon C*. link

46. ACS Chemical Neuroscience. 2002;11(12):1801. PyrPeg, a blood-brain barrier-penetrating two-photon imaging probe, selectively detects neuritic plaques, not tau aggregates. Choi J-W, Ju YH, Choi Y, Hyeon SJ, Gadhe CG, Park J-H, Kim MS, Baek S, Kim Y, Park KD, Pae AN, Ryu H, Lee CJ*, Cho BR*. link

47. Applied Biological Chemistry. 2020;63:22. Investigation of memory-enhancing botanical mixture and their isolated compounds for inhibition of amyloid-β and tau aggregation. Baek S, Park S, Shin J, Lee J-S, Kim HY, Han G, Kim Y*. link

48. Angewandte Chemie International Edition. 2020;59(28):11491 . Discovery of chemicals to either clear or indicate amyloid aggregates by targeting memory‐impairing anti‐parallel Aβ dimers. Lee JC, Kim HY, Lee S, Shin J, Kim HV, Kim K, Baek S, Lee D, Jeon H, Kim D, Yang S-H, Han G, Park K, Choi J, Park J, Moss JA, Janda KD, Kim Y*. (Hot Paper). link

49. PLoS ONE. 2020;15(3):e0230277. Destruction of ERP responses to deviance in an auditory oddball paradigm in amyloid infusion mice with memory deficits. Kim B, Shin J, Kim Y*, Choi JH*. link

50. Dementia and Neurocognitive Disorders. 2020;19(1):e5.Alzheimer's Disease Diagnosis Using Misfolding Proteins in Blood. Lee H, Ugay D, Hong S, Kim Y*. link

51. Sensors and Actuators B. 2020;308:127710. Gold nanoparticles assisted sensitivity improvement of interdigitated microelectrodes biosensor for amyloid-β detection in plasma sample. Yoo YK, Kim G, Park D, Kim J, Kim Y, Kim HY, Yang S-H, Lee JH, Hwang KS*. link

52. PLoS ONE. 2020;15(1):e0227618. Alterations of aqueous humor Aβ levels in Aβ-infused and transgenic mouse models of Alzheimer disease. Kwak DE, Ko T, Koh HS, Ji YW, Shin J, Kim K, Kim HY, Lee H-K*, Kim Y*. link

53. Current Biology. 2020;30:1. Aberrant tonic inhibition of dopaminergic neuronal activity causes motor symptoms in animal models of Parkinson’s disease. Heo JY, Nam M-H, Yoon HH, Kim J, Hwang YJ, Won W, Woo DH, Lee JA, Park H-J, Jo S, Lee MJ, Kim S, Shim J-E, Jang D-P, Kim KI, Hu SH, Jeong JY, Kowall NW, Lee J, Im H, Park JH, Jang BK, Pak KD, Lee HJ, Shin H, Cho I-J, Hwang EM, Kim Y, Kim HY, Oh SJ, Lee SU, Peak SH, Yoon JH, Jin BK, Kweon GY, Shim I, Hwang O, Ryu H*, Jeon SR*, Lee CJ*. link

2019

54. Archives of Pharmacal Research. 2019;42(8):647. Preventive approach for overcoming dementia. Lee H, Kim D, Lee W, Kim HY*, Kim Y*. link

55. Experimental & Molecular Medicine. 2019;51:53. Diagnosis of Alzheimer’s disease utilizing amyloid and tau as fluid biomarkers. Lee JC, Kim SJ, Hong S, Kim Y*. link
    Springer Nature 2019 highlights, a selection of 2019's highly downloaded research in Cell Biology and Biochemistry link

56. ACS Chemical Neuroscience. 2019;10(6):2647. Fluorescence chemicals to detect insoluble and soluble amyloid-β aggregates. Lee D, Kim SM, Kim HY*, Kim Y*. link

57. ACS Chemical Neuroscience. 2019;10(6):3031. Fluorescent 1,4-Naphthoquinones to visualize diffuse and dense-core amyloid plaques in APP/PS1 transgenic mouse brains. Shin NN, Jeon H, Jung Y, Baek S, Lee S, Yoo HC, Bae GH, Park K, Yang S-H, Han JM, Kim I*, Kim Y*. link

58. Science Advances. 2019;5(4):eaav1388. Comparative analyses of plasma amyloid-β levels in heterogeneous and monomerized states by interdigitated microelectrode sensor system. Kim Y*, Yoo YK, Kim HY, Roh JH, Kim J, Baek S, Lee JC, Kim HJ, Chae M-S, Jeong D, Park D, Lee S, Jang H, Kim K, Lee JH, Byun BH, Park SY, Ha JH, Lee KC, Cho WW, Kim J-S, Koh J-Y, Kim SM, Hwang KS. link

59. Scientific Reports. 2019;9:4183. A small molecule Nec-1 directly induces amyloid clearance in the brains of aged APP/PS1 mice. Yang S-H, Shin J, Shin N, Hwang J-H, Hong S-C, Park K, Lee JW, Lee S, Baek S, Kim K, Cho I, Kim Y*. link

60. ACS Central Science. 2019;5(2):209. Frontiers in probing Alzheimer’s disease biomarkers with fluorescent small molecules. Jun YW, Cho SW, Jung J, Huh Y, Kim Y*, Kim D*, Ahn KH*. link

61. Biosensors and Bioelectronics. 2019;128:166. Dielectrophoresis-based filtration effect and detection of amyloid beta in plasma for Alzheimer's disease diagnosis. Kim HJ, Park D, Baek S, Yang S-H, Kim Y, Lim SM, Kim J*, Hwang KS*. link

2018

62. Nano Convergence. 2018;5(1):38. Peptide-nanoparticle conjugates: a next generation of diagnostic and therapeutic platforms? Jeong WJ, Bu J, Kubiatowicz LJ, Chen SS, Kim Y, Hong S*. link

63. Scientific Reports. 2018;8(1):11589. TNF-α increases the intrinsic excitability of cerebellar Purkinje cells through elevating glutamate release in Bergmann Glia. Shim HG, Jang SS, Kim SH, Hwang EM, Min JO, Kim HY, Kim Y, Ryu C, Chung G, Kim Y, Yoon BE*, Kim SJ*. link

64. Sensors. 2018;18(6):E1738. Multifunctionalized reduced graphene oxide biosensors for simultaneous monitoring of structural changes in amyloid-β 40. Jeong D, Kim J, Chae MS, Lee W, Yang SH, Kim Y, Kim SM, Lee JS, Lee JH, Choi J, Yoon DS, Hwang KS*. link

65. Scientific Reports. 2018;8:1331. Four-week individual caging of male ICR mice alters body composition without change in body mass. Shin J, Woo J, Cho Y, Choi YH, Shin NN, Kim Y*. link

66. PROTEOMICS. 2018;18(1):1700302. Identification of plasma membrane glycoproteins specific to human glioblastoma multiforme cells using lectin arrays and LC-MS/MS. Park YE, Yeom J, Kim Y, Lee HJ, Han KC, Lee ST, Lee C, Lee JE*. link

2017

67. Molecular Pharmaceutics. 2017;14(9):3114. Preliminary PET study of 18F-FC119S in normal and Alzheimer’s disease models. Oh SJ, Kim MH, Han SJ, Kang KJ, Ko IO, Kim Y, Park JA, Choi JY, Lee KC, Chi DY, Lee YJ, Kim KM*. link

68. Advances in Experimental Medicine and Biology. 2017;975:233. Taurine directly binds to oligomeric Ab and recovers cognitive deficits in Alzheimer model mice. Jang H, Lee S, Choi SL, Kim HY, Baek S, Kim Y*. link

69. Advances in Experimental Medicine and Biology. 2017;975:225. Taurine-carbohydrate derivative stimulates fibrillogenesis of amyloid-β and reduce Alzheimer-like behaviors. Kim HY, Yang S-H, Yoon J, Jang H, Baek S, Kim SH, Kim Y*. link

70. Scientific Reports. 2017;7:8882. A highly sensitive plasma-based amyloid-β detection system through medium-changing and noise cancellation system for early diagnosis of the Alzheimer’s disease. Yoo YK, Kim J, Kim G, Kim Y, Kim HY, Lee S, Cho WW, Kim S, Lee S-M, Lee BC, Lee JH, Hwang KS*. link

71. Biosensors and Bioelectronics. 2017;92:610. Enhancing surface functionality of reduced graphene oxide biosensors by oxygen plasma treatment for Alzheimer's disease diagnosis. Chae MS, Kim J, Jeong D, Kim Y, Roh JH, Lee SM, Heo Y, Kang JY, Lee JH, Yoon DS, Kim TG, Chang ST, Hwang KS*. link

72. EMBO Molecular Medicine. 2017;9:61. Nec-1 alleviates cognitive impairment with reduction of Aβ and tau abnormalities in APP/PS1 mice. Yang S-H, Lee DK, Shin J, Lee S, Baek S, Kim J, Jung H, Hah J-M, Kim Y*. link

2016

73. Scientific Reports. 2016;6:34165. Rapid and sustained cognitive recovery in APP/PS1 transgenic mice by co-administration of EPPS and donepezil. Kim HY, Kim HV, Lee DK, Yang S-H, Kim Y*. link

74. Scientific Reports. 2016;6:34922. Cell surface GRP78 as a biomarker and target for suppressing glioma cells. Kang BR, Yang S-H, Chung B-R, Kim W, Kim Y*. link

75. Advanced Functional Materials. 2016;26:7057 (Cover). Multifunctional photonics nanoparticles for crossing the blood–brain barrier and effecting optically trackable brain theranostics. Singh A, Kim A, Kim Y, Jeong K, Kang CS, Kim Y, Koh J, Mahajan SD, Prasad PN*, Kim S*. link

76. Scientific Reports. 2016;6:31276. Wafer-scale high-resolution patterning of reduced graphene oxide films for detection of low concentration biomarkers in plasma. Kim J, Chae M-S, Lee SM, Jeong D, Lee JB, Lee JH, Kim Y, Chang ST*, Hwang KS*. link

77. Journal of Visualized Experiments. 2016;109:e53308. Intracerebroventricular injection of amyloid-β peptides in normal mice to acutely induce Alzheimer-like cognitive deficits. Kim HY, Lee DK, Chung B-R, Kim HV, Kim Y*. link

78. Scientific Reports. 2016;6:20185. Age-dependent inverse correlations in CSF and plasma amyloid-β(1-42) concentrations prior to amyloid plaque deposition in the brain of 3xTg-AD mice. Cho SM, Lee S, Yang S-H, Kim HY, Lee MJ, Kim HV, Kim J, Baek S, Yun J, Kim D, Kim YK, Cho Y, Woo J, Kim TS, Kim Y*. link

2015

79. Nature Communications. 2015;6:8997. EPPS rescues hippocampus-dependent cognitive deficits in APP/PS1 mice by disaggregation of amyloid-β oligomers and plaques. Kim HY, Kim HV, Jo S, Choi SY, Lee CJ, Park JK, Kim DJ*, Kim Y*. link

80. Scientific Reports. 2015;5:15703. Abnormalities of plasma cytokines and spleen in senile APP/PS1/Tau transgenic mouse model. Yang S-H, Kim J, Lee MJ, Kim Y*. link

81. Cell Reports. 2015;12(8):1244-51. Amyloid-β oligomers may impair SNARE-mediated exocytosis by direct binding to syntaxin 1a. Yang Y, Kim J, Kim HY, Ryoo N, Lee S, Kim Y, Rhim H, Shin YK*. link

82. Bulletin of the Korean Chemical Society. 2015;36(8):2147-2149. Anti-amyloidogenic approach to access amyloid-β(1–42) in Fmoc solid-phase synthesis. Lee S, Kim Y*. link

83. Bulletin of the Korean Chemical Society. 2015;36(5):1528-1531. Real-time imaging reveals glioblastoma suppression effects of curcumin in mouse brains. Kim W, Kim HY, Woo J, Rhim HJ, Kang BR, Lee Y-D, Kim S, Kim JY, Choi E-J, Kim K-S, Kim DJ, Kim Y*. link

84. Journal of the Korean Society for Applied Biological Chemistry. 2015;58(2):243-248. Real-time imaging of glioblastoma using bioluminescence in a U-87 MG xenograft model mouse. Kim W, Kang BR, Kim HY, Cho SM, Lee Y-D, Kim JY, Kim DJ, Kim Y*. link

85. Bulletin of the Korean Chemical Society. 2015;36(1):413-416. Bis-styrylnaphthalene and bis-styrylnaphthyridine derivatives with high binding affinity to β-amyloid fibrils. Lee YR, Kim Y, Yoo KH*. link

2014

86. Scientific Reports. 2014;4:7467. Taurine in drinking water recovers learning and memory in the adult APP/PS1 mouse model of Alzheimer's disease. Kim HY, Kim HV, Yoon JH, Kang BR, Cho SM, Lee S, Kim JY, Kim JW, Cho Y, Woo J, Kim Y*. link

87. The Journal of Physiology. 2014;592(22):4951-68. Glial GABA, synthesized by monoamine oxidase B, mediates tonic inhibition. Yoon BE, Woo J, Chun YE, Chun H, Jo S, Bae JY, An H, Min JO, Oh SJ, Han KS, Kim HY, Kim T, Kim Y, Bae YC, Lee CJ*. link

88. Scientific Reports. 2014;4:6777. Correlations of amyloid-β concentrations between CSF and plasma in acute Alzheimer mouse model. Cho SM, Kim HV, Lee S, Kim HY, Kim W, Kim TS, Kim DJ, Kim Y*. link

89. Analytica Chimica Acta. 2014;840:1-9. Detection and quantification of plasma amyloid-β by selected reaction monitoring mass spectrometry. Kim JS1, Ahn HS, Cho SM, Lee JE, Kim Y, Lee C*. link

90. Nature Medicine. 2014;20(8):886-96. GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease. Jo S, Yarishkin O, Hwang YJ, Chun YE, Park M, Woo DH, Bae JY, Kim T, Lee J, Chun H, Park HJ, Lee da Y, Hong J, Kim HY, Oh SJ, Park SJ, Lee H, Yoon BE, Kim Y, Jeong Y, Shim I, Bae YC, Cho J, Kowall NW, Ryu H, Hwang E, Kim D, Lee CJ*. link

91. PLoS One. 2014;9(4):e95733. Aminostyrylbenzofuran directly reduces oligomeric amyloid-β and reverses cognitive deficits in Alzheimer transgenic mice. Lee SH, Kim Y (co-first), Kim HY, Kim YH, Kim MS, Kong JY, Lee MH, Kim DJ*, Ahn YG*. link

2013

92. PLoS One. 2013;8(12):e81682. Bimolecular fluorescence complementation; lighting-up tau-tau interaction in living cells. Tak H, Haque MM, Kim MJ, Lee JH, Baik JH, Kim Y, Kim DJ, Grailhe R, Kim YK*. link

93. Bioorganic & Medicinal Chemistry Letters. 2013;23(21):5882-6. 2-Phenylbenzofuran derivatives alleviate mitochondrial damage via the inhibition of β-amyloid aggregation. Lee YS, Kim HY, Youn HM, Seo JH, Kim Y, Shin KJ*. link

94. Bioorganic & Medicinal Chemistry Letters. 2013;23(11):3467-9. Therapeutic and pharmacokinetic characterizations of an anti-amyloidogenic bis-styrylbenzene derivative for Alzheimer's disease treatment. Byeon SR, Kim HV, Jeon M, Ahn YG, Kim MS, Kong JY, Kim HY, Kim Y, Kim DJ*. link

95. Bulletin of the Korean Chemical Society. 2013;34(1):29-30. Wide ranged fluorescent molecular weight size markers for electrophoresis. Park JW, Kim MJ, Lee K-J, Kim Y*. link

96. Bulletin of the Korean Chemical Society. 2013;34(1):287-290. Reactive fluorescence dyes with vinylsulfone group indicating pH perturbation of biomolecules. Park JW, Kim DJ, Lee K-J, Kim Y*. link

97. Amyloid. 2013;20(1):7-12. Amelioration of Alzheimer's disease by neuroprotective effect of sulforaphane in animal model. Kim HV, Kim HY, Ehrlich HY, Choi SY, Kim DJ, Kim Y*. link

2012

98. Bioorganic & Medicinal Chemistry. 2012;20(16):4921-35. Small molecules that protect against β-amyloid-induced cytotoxicity by inhibiting aggregation of β-amyloid. Lee YS, Kim HY, Kim Y, Seo JH, Roh EJ, Han H, Shin KJ*. link

99. Amyloid. 2012;19(3):133-7. Efficient access to highly pure β-amyloid peptide by optimized solid-phase synthesis. Choi JW, Kim HY, Jeon M, Kim DJ, Kim Y*. link

2010

100. Bioconjugate Chemistry. 2012;23(3):350-62. Novel cyanine dyes with vinylsulfone group for labeling biomolecules. Park JW, Kim Y, Lee KJ, Kim DJ*. link

101. Bioorganic & Medicinal Chemistry. 2010;18(22):7724-30. Synthesis and evaluation of stilbene derivatives as a potential imaging agent of amyloid plaques. Hong MC, Kim YK, Choi JY, Yang SQ, Rhee H, Ryu YH, Choi TH, Cheon GJ, An GI, Kim HY, Kim Y, Kim DJ, Lee JS, Chang YT, Lee KC*. link

102. Journal of Alzheimers Disease. 2010;22(1):73-85. Regulation of in vitro Aβ1-40 aggregation mediated by small molecules. Kim HY, Kim Y, Han G, Kim DJ*. link

2009

103. Current Pharmaceutical Design. 2009;15(6):637-58. Multivalent & multifunctional ligands to beta-amyloid. Kim Y, Lee JH, Ryu J, Kim DJ*. link

2008

104. Bioorganic & Medicinal Chemistry Letters. 2008;18(20):5591-3. Aminostyrylbenzofuran derivatives as potent inhibitors for Abeta fibril formation. Byun JH, Kim H, Kim Y, Mook-Jung I, Kim DJ, Lee WK, Yoo KH*. link

105. Bioorganic & Medicinal Chemistry Letters. 2008;18(20):5701-4. [18F]-labeled isoindol-1-one and isoindol-1,3-dione derivatives as potential PET imaging agents for detection of beta-amyloid fibrils. Lee JH, Byeon SR, Kim Y, Lim SJ, Oh SJ, Moon DH, Yoo KH, Chung BY, Kim DJ*. link

2007

106. Molecular Pharmaceutics. 2007;4(3):435-47. Mechanistic studies of a peptidic GRP78 ligand for cancer cell-specific drug delivery. Liu Y, Steiniger SC, Kim Y, Kaufmann GF, Felding-Habermann B, Janda KD*. link

2006

107. Biochemistry. 2006;45(31):9434-44. Targeting heat shock proteins on cancer cells: selection, characterization, and cell-penetrating properties of a peptidic GRP78 ligand. Kim Y, Lillo AM, Steiniger SC, Liu Y, Ballatore C, Anichini A, Mortarini R, Kaufmann GF, Zhou B, Felding-Habermann B, Janda KD*. link

108. Toxicon. 2006;47(8):901-8. A cyclic peptide-polymer probe for the detection of Clostridium botulinum neurotoxin serotype A. Ma H, Zhou B, Kim Y (co-first), Janda KD*. link

2005

109. Molecular Pharmaceutics. 2005;2(6):528-35. A contiguous stretch of methionine residues mediates the energy-dependent internalization mechanism of a cell-penetrating peptide. Kim Y, Lillo A, Moss JA, Janda KD*. link

110. Journal of the American Chemical Society. 2005;127(2):538-9. A dimerization "switch" in the internalization mechanism of a cell-penetrating peptide. Moss JA, Lillo A, Kim Y, Gao C, Ditzel H, Janda KD*. link

2004

111. The Journal of Organic Chemistry. 2004;69(22):7776-8. Biological tuning of synthetic tactics in solid-phase synthesis: application to Aβ(1−42). Kim Y, Moss JA, Janda KD*. link

2002

112. Bulletin of the Korean Chemical Society. 2002;23(11):1509-1510. Single resin bead kinetics using real time fluorescence measurements. Parikh PB, Kim Y, Chang YT*. link

113. Journal of Combinatorial Chemistry. 2002;4(3):204-8. Comparative resin kinetics using in situ fluorescence measurements. Walsh DP, Pang C, Parikh PB, Kim Y, Chang YT. link

1. Aging Mechanisms: Longevity, Metabolism, and Brain Aging. Springer, 2015. ISBN 978-4-431-55763-0. Chapter 22, Immunotherapeutic approaches against amyloid-β in drug discovery for Alzheimer’s disease. Yang S-H, Kim J, Kim Y*. link

2. 2.Brain Damage – Bridging Between Basic Research and Clinics. InTech, 2012. ISBN 978-953-51-0375-2. Chapter 5, Pathology of neurodegenerative disease. Kim Y, Kim YK,  Hwang O, Kim DJ*. link